Giant-cell arteritis (GCA) is a systemic inflammatory vasculitis of unknown etiology commonly Horton’s disease is a clinical entity caused by GCA mainly of temporal arteries (temporal arteritis). . Hunder GG, Bloch DA, Michel BA, et al. Dr. med.,3 and Peter Lamprecht, Prof. .. in acute temporal arteritis, showing hypoechoic wall thickening (arrows), .. Horton BT, Magath TB, Brown GE. Horton was a member of the International Cluster Headache Research Group from .. Horton emphasized that temporal arteritis is not a localized disease confined to the .. Musings on medical research with a note on my last talk with Dr. Will.

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Giant cell arteritis is an inflammation of the lining of your arteries. Most often, it affects the arteries in your head, especially those in your temples. For this reason, giant cell arteritis is sometimes called temporal arteritis.

The Diagnosis and Treatment of Giant Cell Arteritis

Giant cell arteritis frequently causes headaches, scalp tenderness, jaw pain and vision problems. Untreated, it can lead to blindness. Prompt treatment with corticosteroid medications usually relieves symptoms of giant cell arteritis and might prevent loss of vision. You’ll likely begin to feel better within days of starting treatment.

But even with treatment, relapses are common. You’ll need to visit your doctor regularly for checkups and treatment of any side effects from taking corticosteroids. The most common symptoms of giant cell arteritis are head pain and tenderness — often severe — that usually affects both temples.


Head pain can progressively worsen, come and go, or subside temporarily.

Pain and stiffness in the neck, shoulders or hips are common symptoms of a related disorder, polymyalgia rheumatica.

About 50 percent of people with giant cell arteritis also have polymyalgia rheumatica. Hrton you develop a new, persistent headache or any of the signs and symptoms listed above, see your doctor without delay. If you’re diagnosed with giant cell arteritis, starting treatment as soon as possible can usually help prevent vision loss. With giant cell arteritis, the lining of arteries becomes inflamed, causing them to swell.

This swelling narrows your blood vessels, reducing the amount of blood — and, therefore, oxygen twmporal vital nutrients — that reaches your body’s tissues.

Clinical Aspects of the Temporal Arteritis

Almost any large or medium-sized artery can be affected, but swelling most often occurs in the arteries in the temples. These are just in front of your ears and continue up hotton your scalp.

What causes these arteries to become inflamed isn’t known, but it’s thought to involve abnormal attacks on artery walls by the immune system. Certain genes and environmental factors might increase your susceptibility to the condition.

An aneurysm is a bulge that forms in a weakened blood vessel, usually in the large artery that runs temporql the center of your chest and abdomen aorta.

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Giant cell arteritis – Symptoms and causes – Mayo Clinic

An aortic aneurysm might burst, causing life-threatening internal bleeding. Because this complication can occur even hprton after the diagnosis of giant cell arteritis, your doctor might monitor your aorta with annual chest X-rays or other imaging tests, such as ultrasound and CT.

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Giant-cell arteritis

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Overview Giant cell arteritis is an inflammation of the lining of your arteries. Giant cell arteritis Giant cell arteritis causes inflammation of certain arteries, especially those near the temples. Request an Appointment at Mayo Clinic.

References Docken WP, et al. Clinical manifestations of giant cell arteritis. American College of Rheumatology. Diagnosis of giant cell arteritis. Dejaco C, et al. Giant cell arteritis and polymyalgia rheumatic: Current challenges and opportunities.

Genetic and Rare Diseases Information Center. FDA approves Genentech’s Actemra for giant cell arteritis. Merck Manual Professional Version. Treatment of giant cell arteritis. Mayo Clinic Marketplace Check out these best-sellers and special offers on books and newsletters from Mayo Clinic.